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[reference.com](https://www.reference.com/business-finance/subjects-need-study-become-lawyer-9f24fa369d533f4f?ad=dirN&qo=serpIndex&o=740005&origq=lawyer+article)Typically the primary limiting important amino acid in progress and manufacturing. [Mutation](https://system.yb-twc.com/git/rossspradlin22/6330solicitor-article/-/issues/1) of Tyr245 or Tyr305 in SET7/9 (Figure 4b ) alters its specificity from an H3 K4 mono-methylase to a tri- and di-methylase, respectively sixteen , 21 , whereas an Phe281Tyr mutation in the lysine-binding pocket of DIM-5 (Figure 4c ) converts this protein to an H3 K9 mono- or di-methylase sixteen These mutations exemplify the F/Y change (Determine 1 ) that establishes SET-domain product specificities. |
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